A curved D-type optical fiber sensor (OFS) combined with a microfluidic chip is proposed.\nThis OFS, based on surface plasmon resonance (SPR) of the Kretchmannââ?¬â?¢s configuration, is applied\nas a biosensor to measure the concentrations of different bio-liquids such as ethanol, methanol, and\nglucose solutions. The SPR phenomenon is attained by using the optical fiber to guide the light source\nto reach the side-polished, gold-coated region. Integrating this OFS with a polymethylmethacrylate\n(PMMA)-based microfluidic chip, the SPR spectra for liquids with different refractive indices are\nrecorded. Experimentally, the sensitivity of the current biosensor was calculated to be in the order of\n10âË?â??5 RIU. This microfluidic chip-integrated OFS could be valuable for monitoring subtle changes in\nbiological samples such as blood sugar, allergen, and biomolecular interactions.
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